What is androgenetic alopecia? Androgenetic alopecia is the most common hair loss cause .
One of the proved causes of androgenetic alopecia is the excessive presence of dihydrotestosterone (or DHT) in the hair follicle. The DHT is extremely dangerous to the follicle: at first it shortens the growth fase of the hair, then it miniaturizes the follicle (and the hairs get thinner and thinner), and finally it leads to a complete atrophy. The DHT is produced by the transformation of the androgenic hormones due to the effect of the 5-alfa-reductasi enzyme.
Testosterone is the androgenic hormone par excellence. It is a male hormone but is also present in women. Among men testosterone is secreted mostly by the interstitial cells of the testicles (about 8 mg. a day), while among women the secretion is lower and caused by the ovaries and the adrenal gland. The transformation of the androgenic hormones into DHT takes place inside the sebaceous gland of the follicles and not inside a certain area of the scalp; this is proved by the fact that the hairs transplanted from the side and posterior areas of he scalp, that are not subject to androgenetic alopecia, into areas subject to it, the transplanted hair never stops growing.
DHT is not the only cause of androgenetic alopecia. Immunological factors contribute to it: once DHT starts working, the immune system attacks the follicles, thus jeopardizing the right hair production.
Androgenetic alopecia, seborrheic alopecia, common baldness, hereditary baldness, male baldness….
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